Evolocumab lowers LDL cholesterol

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Evolocumab lowers LDL-C safely and effectively when self-administered in the at-home setting

Evolocumab has been shown to consistently reduce low-density lipoprotein cholesterol (LDL-C) across populations. The phase 3 studies included administration in the home-use and in-clinic settings but did not specifically evaluate the feasibility of home-use administration. Two clinical studies enrolled patients with hypercholesterolemia or mixed dyslipidemia on statin therapy and with/without e...

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Beta-glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations.

BACKGROUND beta-Glucan can reduce serum concentrations of total and LDL cholesterol. The mechanism of this action is not clear, however, and it is difficult to predict the cholesterol-lowering effect of a food product enriched with beta-glucan. OBJECTIVES We examined the effects of a beta-glucan-enriched fruit juice on serum lipids and lipoproteins and on markers of cholesterol absorption (se...

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ژورنال

عنوان ژورنال: Nature Reviews Cardiology

سال: 2014

ISSN: 1759-5002,1759-5010

DOI: 10.1038/nrcardio.2014.169